2009年9月-2014年7月 清华大学工程物理系,博士
2005年9月-2009年7月 东南大学生物科学与医学工程学院,学士
2021年2月至今 北京师范大学物理学系,教授
2018年7月-2020年10月 美国耶鲁大学放射与生物医学成像系,副研究员(Associate Research Scientist)
2014年10月-2018年6月 美国耶鲁大学放射与生物医学成像系,博士后(Postdoctoral Associate)
2011年5月-2012年1月 美国德克萨斯州立大学M.D. Anderson Cancer Center成像物理学系,访问学生
课题组的研究方向为医学物理、成像算法。
主要研究内容包括:PET和SPECT成像系统的设计和蒙特卡洛模拟、计算机图像重建和GPU加速、定量成像过程中的物理效应校正、药代动力学成像等。
普通物理实验
国家级青年人才项目,主持
科技部国家重点研发计划项目,课题负责人,2022-2025
国家自然科学基金青年项目,主持,2024-2026
北京市自然科学基金重点研究专题项目,课题负责人,2022-2026
2022:Ones to Watch, Society of Nuclear Medicine and Molecular Imaging (SNMMI)
2020: Scientific Session Young Investigator Competition Finalist, American Society of Nuclear Cardiology (ASNC) Annual Meeting
2019: Physics, Instrumentation and Data Science Young Investigator Award Honorable Mention, Society of Nuclear Medicine and Molecular Imaging (SNMMI) Annual Meeting
2019: Alavi–Mandell Award for the publication entitled “Simplified Quantification and Acquisition Protocol of 123I-mIBG Dynamic SPECT”
2017: Alavi–Mandell Award for the publication entitled “Quantitative Analysis of Dynamic 123I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method”
每年拟招收硕士生1-2名,博士生1-2名,同时招收博士后。欢迎对医学物理和成像算法感兴趣的同学邮件联系。
代表论文(查看完整论文列表)
1. Wu J, Liu C. Dedicated Tomographic Single Photon Systems. (Book Chapter). In Handbook of Nuclear Medicine and Molecular Imaging for Physicists, pp. 315-332. CRC Press, 2022.
2. Wu J*, Liu H, Ye Q, Gallezot JD, Naganawa M, Miao T, Lu Y, Chen MK, Esserman DA, Kyriakides TC, Carson RE,Liu C*. Generation of parametric Ki images for FDG PET using two 5-min scans. Medical Physics. 2021, 48(9):5219-5231.
3. Liu H, Wu J*, Lu W, Onofrey JA, Liu YH, Liu C*. Noise reduction with cross-tracer and cross-protocol deep transfer learning for low-dose PET. Physics in Medicine and Biology. 2020, 65(18):185006.
4. Wu J#, Boutagy NE#, Cai Z, Lin SF, Zheng MQ, Feher A, Stendahl JC, Kapinos M, Gallezot JD, Liu H, Mulnix T, Zhang W, Lindemann M, Teng JK, Miller EJ, Huang Y, Carson RE, Sinusas AJ, Liu C*. Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals. Journal of Nuclear Cardiology. 2020 May 15. Online ahead of print. (# contributed equally)
5. Liu H, Thorn S, Wu J*, Fazzone-Chettiar R, Sandoval V, Miller EJ, Sinusas AJ, Liu YH*. Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients. Journal of Nuclear Cardiology. 2020 Jul 26. Online ahead of print.
6. Toczek J#, Wu J#, Hillmer AT, Han J, Esterlis I, Cosgrove KP, Liu C, Sadeghi MM*. Accuracy of arterial [18F]-Fluorodeoxyglucose uptake quantification: A kinetic modeling study. (Brief Report). Journal of Nuclear Cardiology. 2020, 27(5): 1578–1581. (# contributed equally)
7. Wu J*, Liu C*. Recent advances in cardiac SPECT instrumentation and imaging methods. (Topical Review). Physics in Medicine andBiology. 2019, 64(6): 06TR01.
8. Liu H, Wu J*,Sun JY, Wu TH, Fazzone-Chettiar R, Thorn S, Sinusas AJ, Liu YH*. A robust segmentation method with triple-factor non-negative matrix factorization for myocardial blood flow quantification from dynamic 82Rb positron emission tomography. Medical Physics. 2019, 46(11): 5002-5013.
9. Wu J, Gallezot JD, Lu Y, Ye Q, Liu H, Esserman DA, Kyriakides TC, Thorn SL, Zonouz TH, Liu YH, Lampert RJ, Sinusas AJ, Carson RE, Liu C*. Simplified quantification and acquisition protocol of 123I-mIBG dynamic SPECT. Journal of Nuclear Medicine. 2018, 59(10):1574-1580.
10. Boutagy NE#, Wu J#, Cai Z, Zhang W, Booth CJ, Pfau D, Mulnix T, Liu Z, Miller EJ, Young LH, Carson RE, Huang Y, Liu C, Sinusas AJ*. In vivo reactive oxygen species detection with a novel PET tracer, 18F-DHMT, allows for early detection of anthracycline-induced cardiotoxicity in rodents. JACC: Basic to Translational Science. 2018, 3(3): 378-390. (# contributed equally)
11. Wu J*, Liu H, Zonouz TH, Sandoval VM, Mohy-Ud-Din H, Lampert RJ, Sinusas AJ, Liu C, Liu YH*. A blind deconvolution method incorporated with anatomical-based filtering for partial volume correction: validations with 123I-mIBG cardiac SPECT/CT. Medical Physics. 2017,44(12): 6435-6446.
12. Wu J, Lin SF, Gallezot JD, Chan C, Prasad R, Thorn SL, Stacy MR, Huang Y, Zonouz TH, Liu YH, Lampert RJ, Carson RE, Sinusas AJ, Liu C*.Quantitative analysis of dynamic 123I-mIBG SPECT imaging data in healthy humans with a population-based metabolite correction method. Journal of Nuclear Medicine. 2016, 57(8):1226-1232.